Brain Research Lab

At the Brain Research Lab, our team of research professors, post-doctoral researchers and graduate student investigators study the multiple actions of progesterone and its metabolites in a variety of central nervous system disorders.

In close collaboration with physicians and scientists here at Emory and around the world, we conduct basic and translational research.

Our research has now successfully moved to clinical testing in the following human trials:

  • Two independent, Phase II clinical trials for safety and efficacy of progesterone found that in severely brain-injured patients, mortality was reduced by almost 60% compared to standard care, and functional outcomes were significantly better. (source)
  • ProTECT III, sponsored by the National Institutes of Health (NIH), is a Phase 3, multi-center, national trial using progesterone to treat moderate to severe TBI.
  • SyNAPSe, a Phase 3 trial supported by BHR Pharma, is currently underway in the United States, Europe, Israel, Russia, Singapore and China.